Original Article

[2019]
    Takeshi Hori *, Kei Yamane, Takayuki Anazawa, Osamu Kurosawa, Hiroo Iwata:
    Compact fluidic system for functional assessment of pancreatic islets.
    Biomedical Microdevices. 2019 Nov 4;21(4):91

[2018]
    Takeshi Hori * and Osamu Kurosawa:
    A three-dimensional cell culture method with a micromesh sheet and its application to hepatic cells.
    Tissue Engineering Part C Methods. 2018;24(12):730-39
 

    Takeshi Hori, Kosuke Saito, Rick Moore, Gordon P. Flake, and Masahiko Negishi:
    Nuclear receptor CAR suppresses GADD45B-p38 MAPK signaling to promote phenobarbital-induced proliferation in mouse liver.
    Molecular Cancer Research. 2018 Aug;16(8):1309-1318
    Highlights
    NIEHS News

[2016]
    Takeshi Hori, Rick Moore, and Masahiko Negishi:
    p38 MAP kinase links CAR activation and inactivation in the nucleus via phosphorylation at threonine 38
    Drug Metabolism and Disposition. 2016 Jun;44(6):871-6. PMID: 27074912
    Takeshi Hori, Liangjing Jin, Ayako Fujii, Tomomi Furihata, Yuko Nagahara, Kan Chiba, and Masakiyo Hosokawa:
    Dexamethasone-mediated transcriptional regulation of rat carboxylesterase 2 gene.
    Xenobiotica. 2012 Jul;42(7):614-23. PMID: 22235919

[2010]
    Takeshi Hori and Masakiyo Hosokawa:
    DNA methylation and its involvement in carboxylesterase 1A1 (CES1A1) gene expression.
    Xenobiotica. 2010 Feb;40(2):119-28. PMID: 20082576

Presentations

[2019]
    Takeshi Hori:
    Development of cell culture devices using micromesh techniques
    Naigai workshop, Sendai, 2019 September

    Osamu Kurosawa, Takeshi Hori, Nobutaka Tani, Hiroo Iwata:
    The micro mesh culture method realizes the formation and long-term culture of 3D cell sheet capable of enhanced cell function and microscopic observation.
    AIBBC, Kenya, 2019 August

    Takeshi Hori, Kosuke Saito, Rick Moore, Gordon P. Flake, and Masahiko Negishi:
    Nuclear Receptor CAR Suppresses GADD45B-p38 MAPK Signaling to Promote Phenobarbital-induced Proliferation in Mouse Liver.
    The 17th Annual Congress of International Drug Discovery Science & Technology-2019, Kyoto, 2019 July

[2018]
    Osamu Kurosawa, Takeshi Hori, Nobutaka Tani and Hiroo Iwata,:
    Micromesh culture technique enabling cell maturation for the use of organ on a chip.
    MicroTAS 2018, Kaohsiung, Taiwan, 2018 November.

    Takeshi Hori, Osamu Kurosawa, and Hiroo Iwata:
    Micromesh culture to regulate cell function and structure.
    The 25th HAB research organization academic meeting, Tsukuba, Japan. 2018 May.

    Takeshi Hori, Osamu Kurosawa, and Hiroo Iwata:
    Regulation of cell function and structure by a micromesh sheet.
    Pacific Rim Nano Medicine Symposium 2018, Kobe, Japan. 2018 January.

[2016]
    Takeshi Hori, Rick Moore, Kosuke Saito, and Masahiko Negishi:
    Nuclear receptor CAR represses p38 MAPK signaling through its interaction with GADD45B.
    The 21st International Symposium on Microsomes and Drug Oxidations (MDO), Davis, USA. 2016 October.

[2014]
    Takeshi Hori, Tsutomu Sakuma, Sawako Shindo, Rick Moore, and Masahiko Negishi:
    Phosphorylation of VDR at serine 51 in mouse tissues.
    Vitamin D Workshop, Poster presentation. Chicago, USA. 2014 June.

    Masakiyo Hosokawa, Takeshi Hori, Tamihide Matsunaga, and Shigeru Ohmori:
    Dexamethasone mediates transcriptional regulation of carboxylesterase 1A1 gene in human fetal liver cells.
    The 19th North American ISSX Meeting and 29th JSSX Annual Meeting, Poster presentation. San Francisco, USA. 2014 Oct.


[2011]
    Takeshi Hori, Liangjing Jin, Ayako Fujii, Tomomi Furihata, Yuko Nagahara, Kan Chiba, and Masakiyo Hosokawa:
    Transcriptional regulation of rat carboxylesterase 2 gene by dexamethasone.
    The 26th annual meeting of the Japanese Society for the Study of Xenobiotics (JSSX). 2011 Nov.

[2010]
    Takeshi Hori, Tomomi Furihata, Teruko Imai, Kan Chiba, and Masakiyo Hosokawa:
    DNA methylation on carboxylesterase 1A1 (CES1A1) gene in human small intestine.
    The 25th annual meeting of the Japanese Society for the Study of Xenobiotics (JSSX), 2010 Oct.

    Liangjing Jin, Takeshi Hori, Ayako Fujii, Yuko Nagahara, Tomomi Furihata, Kan Chiba, and Masakiyo Hosokawa:
    A molecular mechanism of induction of rat carboxylesterase 2A10 (CES2A10) by dexamethasone.
    The 25th annual meeting of the Japanese Society for the Study of Xenobiotics (JSSX), 2010 Oct.

    Masakiyo Hosokawa, Takeshi Hori, Sachiyo Sudou, Yuma Hatano, Eijirou Kurabayashi, Yasuhiro Uno, and Teruko Imai:
    Tissue specific expression and substrate specificity of carboxylesterase isozymes in humans and experimental animals.
    The 130th annual meeting of the Pharmaceutical Society of Japan, 2010 Mar.

[2009]
    Takeshi Hori and Masakiyo Hosokawa:
    DNA methylation is involved in carboxylesterase 1A1 (CES1A1) gene expression.
    The 24th annual meeting of the Japanese Society for the Study of Xenobiotics (JSSX), 2009 Nov.

    Takeshi Hori, Tomomi Furihata, Kan Chiba, and Masakiyo Hosokawa:
    Involvement of hepatocyte nuclear factor 4α (HNF4α) in transcriptional regulation of the carboxylesterase 1A1(CES1A1) gene.
    The 129th annual meeting of the Pharmaceutical Society of Japan, 2009 Mar.

[2008]
    Koozi Matuoka, Takeshi Hori, and Keiko Sasaki:
    Signaling events for osteoclastic differentiation of human promyelocytic HL60 cells: their augmentation by heparin.
    The 128th annual meeting of the Pharmaceutical Society of Japan, 2008 Mar.

Awards and Honors

[2014]
    Trainee travel award, Vitamin D Workshop, Chicago, USA

Grant

[2018]
    Takeshi Hori:
    Development of organs-on-a-chip as alternatives to animal testing.
    Hoyu, Japan

Other

[2013]
    Takeshi Hori:
    Transcriptional regulation of carboxylesterase gene by glucocorticoid receptors and epigenetic marks.
    Doctoral thesis, 2013 Feb.